Premarin Vaginal Cream 0.625 mg (14gm)

Warning

Side effects

The side effects of this medication include breast tenderness, bloating, weight change, nausea/ vomiting, and headache. You should approach your doctor right away if you experience any of the below-given side effects:

• Vaginal bleeding, such as spotting or recurrent bleeding
• Severe abdominal/ stomach pain 
• Mood changes or mental problems like depression or memory problems
• Swelling feet, ankles, or hands
• Yellowing skin or eyes
• Dark urine
• Increased thirst or urination

However, these side effects fade away with time, and you can treat them if you follow your doctor’s instructions.

Interactions

Although Primarin Vaginal Cream is safe, sometimes there might be some cases where it interacts with medicines or diseases to show side effects.

Drug Interactions

List all medicines you consume and show them to your doctor. You should not start or stop a medication without prior approval from your doctor.

The following list contains the possible drugs that can interact with Premarin Vaginal Cream to produce side effects. 

• Fulvestrant
• Tamoxifen
• Aromatase inhibitors (such as Anastrozole, Exemestane, Letrozole) 
• Tranexamic acid
• Toremifene
• Ospemifene 
• Raloxifene

Disease Interactions

You should not use Premarin Vaginal Cream if you have:

• Undiagnosed vaginal bleeding
• Bleeding disorder
• Liver disease
• Stroke
• Heart attack
• Breast cancer
• Cancer of the cervix/ uterus or vagina

Food Interactions

It is better not to consume grapefruit juice while using Premarin Vaginal Cream.

Precautions

These are the precautions you need to be careful of while using the Premarin Vaginal Cream:

• Missed Dose: If you miss your dose, use only what is necessary for the next dose. Taking an extra dose to compensate for the missed one may harm you. Instead, use it when you remember if it is not time for your next dose yet. You can skip the previous one if it is already time for your next dose
• Overdose: You should consult your doctor if there is an overdose of the cream
• Tell your doctor if you might be allergic to this medication or have any other allergies
• You should tell your doctor your medical history; especially if you have cancer, blood clot, heart disease, stroke, vaginal bleeding (of unknown causes), family medical history, hypothyroidism, seizure, asthma, or hormonal problems
• Do not use tobacco or smoke
• Please don’t stay in the sun for too long, as it may cause parts of your skin to become dark
• Do tell the doctor if you will be confined to bed for a long time or if you have major surgery soon, as it increases the chances of your blood clotting

Storage

You should store this cream at 20-25°C (68-77°F)