A Comprehensive Guide to Levofloxacin Dosage: Tailoring Treatment for Various Infections

Amoha Jha
Medically reviewed by
Dr. Kaushal

Review medical content on WOW Rx Pharmacy, so that accurate drug use information is easily accessible to everybody.
Dr. Akansha is a licensed Clinical Pharmacologist. She possesses remarkable knowledge in Pharmacovigilance, prescription analysis, drug information, and drug safety services. Additionally, she is a keen learner and an educator.

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levofloxacin dosage

Levofloxacin, a member of the Fluoroquinolone antibiotic class, is a versatile medication used to combat many bacterial infections. 

As with any medication, proper dosing of Levofloxacin is essential.

It helps to ensure effective treatment outcomes and prevent potential adverse effects. 

In this comprehensive guide, we will explore the various dosage regimens of Levofloxacin for specific infections.

We will also discuss the considerations for missed doses and available forms of the medication.

Available dosage forms of Levofloxacin

Levofloxacin is available in multiple dosage forms to accommodate various patient needs:

Oral tablets

Levofloxacin tablets are commonly prescribed for infections that can be managed on an outpatient basis. 

They come in strengths of 250 mg, 500 mg, and 750 mg.

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Intravenous (IV) injection

For more severe infections or when oral administration is not feasible, healthcare providers may opt for IV Levofloxacin. 

This form is particularly useful for hospitalized patients.

Levofloxacin dosage for various conditions

Levofloxacin is approved for treating various bacterial infections caused by susceptible organisms. 

It’s important to note that dosages may differ for specific infections.

Levofloxacin dosage can also vary based on the severity of the infection, patient age, renal function, and other factors.

Generally, Levofloxacin dosages are as follows for different conditions:

Urinary Tract Infections (UTIs)

Urinary tract infections are a common reason for prescribing Levofloxacin.Source: Milko_from_Getty_Images_Signature
Levofloxacin dosage for UTI

Urinary tract infections are a common reason for prescribing Levofloxacin. 

The standard Levofloxacin dosage for UTI is usually 250 mg once daily for three days. 

For complicated UTIs or infections involving the kidneys, a higher dose of 750 mg orally or via IV administration once daily for five days may be recommended.


Levofloxacin is often used to treat Community-Acquired Pneumonia. 

A higher dosage of 750 mg orally or intravenously once daily for 7 to 14 days is given, depending on the severity of the infection.

Sinus infections

Levofloxacin can be used to treat sinus infections, particularly those caused by susceptible bacteria. 

A common dosage might be 750 mg orally once daily for five days.


It’s important to note that Levofloxacin is not the first-line treatment for Chlamydia. 

Other antibiotics are generally preferred. 

However, if Levofloxacin is prescribed for Chlamydia, a dosage of 500 mg orally once daily for seven days might be recommended.

Tooth Infections

Levofloxacin may be considered for tooth infections when other antibiotics are not suitable.

Dosages can vary, but a common regimen might involve a higher dosage of upto 1000 mg.


In cases of Appendicitis, Levofloxacin might be used as part of a broader treatment plan, which involves other medications.

Dosages can vary widely based on the severity of the condition and the overall treatment approach.

Skin infections

Levofloxacin helps to prevent the infection from spreading to other body partsSource: shisuka
Skin infections

Levofloxacin can effectively treat various skin infections, including Cellulitis. 

A common dosage, along with other medications, might involve 750 mg intravenously once daily.


For the treatment of Plague, Levofloxacin may be administered as 500 mg orally or via IV once daily. 

This is part of a broader treatment regimen involving other antibiotics.


Treating Endocarditis, which is an infection of the heart valves or the lining of the heart chambers, may require higher doses of Levofloxacin. 

Dosages might range from 500 mg to 1000 mg orally or IV.

Inhalation Anthrax

Inhalation Anthrax is a serious condition, and Levofloxacin is among the antibiotics used in its treatment. 

The recommended dosage is typically 500 mg orally or IV once daily as part of a comprehensive treatment plan.

Throat infections

Levofloxacin dosage for throat infections may vary depending on the specific causative bacteria and the severity of the infection. 

It’s crucial always to follow the dosing instructions provided by your healthcare provider, as changing it may result in unwanted complications.

What to do when you miss a dose

If you miss a dose of Levofloxacin, take it as soon as you remember. 

However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. 

Never double up on doses to make up for a missed one, as this can increase the risk of adverse effects.


Understanding the appropriate Levofloxacin dosage is important when seeking effective treatment for a wide spectrum of bacterial infections. 

Levofloxacin’s versatility, available forms, and dosing flexibility make it a valuable tool in the fight against infections. 

It comes in doses of 250 mg, 500 mg, and 750 mg and can be administered in two ways: orally and intravenously. 

However, it is imperative to strictly adhere to healthcare provider instructions to ensure safety and efficacy.

It is also crucial to exercise caution when a dose is missed. 

Always consult a healthcare professional for personalized guidance in managing infections with Levofloxacin.

Frequently Asked Questions

What is the dose of Levofloxacin for bacterial infection?

The dose of Levofloxacin for a bacterial infection varies based on the specific type and severity of the infection. Generally, it ranges from 250 mg to 750 mg taken orally or via intravenous (IV) administration, typically once daily for a specific duration determined by a healthcare provider.

What should I do if I miss a dose of Levofloxacin?

If you miss a dose of Levofloxacin, take it as soon as you remember. However, if it’s close to your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Never double up on doses, as this can increase the risk of adverse effects.

Are there different dosage forms of Levofloxacin available?

Yes, Levofloxacin is available in different dosage forms to suit various patient needs. It can be obtained in oral tablet forms with strengths of 250 mg, 500 mg, and 750 mg. Additionally, an intravenous injection form is available, primarily used for more severe infections or when oral administration is not feasible.

How do I know the right Levofloxacin dosage for my condition?

Determining the correct Levofloxacin dosage depends on factors such as the specific infection, its severity, patient age, and renal function. It’s essential to consult your healthcare provider, as they will assess your condition and tailor the dosage to ensure effective treatment while minimizing potential side effects.

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