Tadalafil vs Sildenafil: Which One Works Best for You?
Are you looking for an effective Erectile Dysfunction (ED) treatment but confused between the numerous products available in the market? Well, my friend, you are not alone; being confused is normal. But to make things easy, we have prepared a comprehensive comparison article between the best ED medications: Tadalafil and Sildenafil.
They are both PDE5 (Phosphodiesterase type 5) inhibitors that enhance penile blood flow to help maintain an erection and treat ED. These medications can significantly improve your sexual health and quality of life, but understanding the differences between them is crucial for making an informed decision. In this article, we will find which is better, Tadalafil vs Sildenafil, by comparing these two drugs across various aspects, such as effectiveness, cost, duration of drug action, etc., that matter when choosing the right ED medication for you.
Overview of Sildenafil vs Tadalafil for Erectile Dysfunction
| Aspect | Sildenafil | Tadalafil |
|---|---|---|
| Onset of action | Within 30 minutes | 30 minutes to 2 hours |
| Duration of action | Upto 4 hours (approx) | 24 to 36 hours (approx) |
| Dosage flexibility | Available in 10 mg to 100 mg | Available in 2.5 mg to 20 mg |
| Side effects | Muscle aches, bloody nose, diarrhea, difficulty breathing, headache | Headache, flushing, nausea, stuffy nose, muscle aches |
Continue reading to find out more about Tadalafil vs Sildenafil Citrate.
Onset of action
One of the primary differences between Tadalafil and Sildenafil is how quickly they start working. Sildenafil, commonly known by its brand name Viagra, typically begins to work within 30 minutes after ingestion. This makes it ideal for spontaneous encounters where timing is critical.
On the other hand, Tadalafil, marketed under the brand name Cialis, has a slower onset of action. It usually starts working within 30 minutes to 2 hours after taking the medication. However, Tadalafil has a longer window of action, which brings us to our next point.
Duration of action
When it comes to duration, Tadalafil stands out as the winner. While Sildenafil’s effects typically last for around 4 hours, Tadalafil can remain effective for up to 36 hours. This longer duration means you can take medicines such as Tadacip 20mg, containing Tadalafil, without needing to time intimacy quite as precisely.
Cost
Cost can be a crucial factor when choosing between these medications. Here’s a side-by-side comparison of Sildenafil vs Tadalafil cost without insurance:
| Aspect | Sildenafil | Tadalafil |
|---|---|---|
| Quantity | 2 tablet | 8 tablet |
| Dosage | 100 mg | 5 mg |
| Per unit | $4.83 – $16.06 | $4.41 |
| Cost | $9.66 – $32.11 | $35.28 |
However, prices may vary depending on factors such as location, dosage strength, and quantity. You can find the best deals at WowRx – a trusted online pharmacy.
Effectiveness
Sildenafil and Tadalafil are both recognized for their similar effectiveness in addressing ED. In this regard, the Annals of Internal Medicine conducted a research study. It has primarily focused on how PDE5 inhibitors perform compared to a Placebo, which is essentially a sugar pill with no active ingredients.
The study has shown that PDE5 inhibitors, including Sildenafil and Tadalafil, improved erections in 67% to 89% of individuals with ED. In contrast, only 27% to 35% of men experienced improvements when given a Placebo. While these medications might not be pitted against each other in direct comparisons, they exhibit substantial effectiveness in enhancing erectile function.
Dosage flexibility
Regarding dosage options, both Tadalafil and Sildenafil offer various strengths to suit different needs. Sildenafil is available in forms such as an oral tablet, liquid suspension, and powder for reconstitution. It is also available as an injectable solution administered by a healthcare professional. However, Tadalafil is currently only available as an oral medicine.
Sildenafil provides a broader range of doses, offering more flexibility in finding the appropriate dosage. It is available in the following strengths:
- 10 mg
- 10 mg/12.5 mL
- 20 mg
- 25 mg
- 50 mg
- 100 mg
Typically, a single dose of products such as Caverta 100mg is taken once a day, one hour before sexual activity.
On the other hand, Tadalafil is offered in doses ranging from 2.5 mg to 20 mg, providing options for lower doses. The available strengths are:
- 2.5 mg
- 5 mg
- 10 mg
- 20 mg
- 20 mg/5 mL
A typical single dose is 10 mg once a day, one hour before sexual activity.
In summary, Sildenafil offers more dosage options, while Tadalafil demonstrates effectiveness at lower doses.
Side effects
All PDE5 inhibitors, including Sildenafil and Tadalafil, have some common side effects. The usual side effects are mild and may comprise:
- Headache
- Flushing
- Nasal congestion
- Upset stomach (indigestion)
- Muscle pain
However, there are some distinctions to consider. Sildenafil carries a slightly higher risk of causing vision changes compared to Tadalafil. Some Sildenafil users may experience blue-tinted vision, red and blue-speckled vision, and blurred vision as adverse effects on vision.
On the other hand, Tadalafil presents a slightly elevated risk of muscle pain in comparison to Sildenafil. Thus, consult your doctor to know which medication is better for you to treat Erectile Dysfunction. They can suggest it on the basis of our current health conditions and other important factors.
Interactions
Any medication’s interactions are reported in three ways:
- Drug interaction
- Disease interaction
- Food interaction
Here’s a side-by-side comparison of Tadalafil vs Sildenafil number of interactions:
| Interactions | Tadalafil | Sildenafil |
|---|---|---|
| Drug | 307 (33 are major, 177 are moderate, and 97 are minor) | 333 (38 are major, 291 are moderate, and 4 are minor) |
| Disease | 9 | 10 |
| Food | 1 | 2 |
As you can see, Tadalafil has fewer reported drug, disease, and food interactions in comparison with Sildenafil, making it a preferred choice if you take any particular medication, have any health condition, or follow a specific diet.
Prescription requirement
In many areas, Tadalafil and Sildenafil typically require a prescription. This implies that you’ll need medical approval before accessing them. However, in certain countries, specific types of Sildenafil can be obtained without a prescription. Nevertheless, it’s essential to seek advice from a healthcare provider to confirm the suitability of these medications for your needs.
Ratings & reviews
The Sildenafil vs Tadalafil review method is an easy way to know which medicine is more popular among men to treat ED. Based on the user ratings on Drugs.com, one of the largest medicine information websites, here are the ratings and reviews of both medicines:
| Medicine | Tadalafil | Sildenafil |
|---|---|---|
| Average rating | 8.4/10 | 8.3/10 |
| Number of reviews | 747 | 481 |
| Positive experience | 81% | 78% |
| Negative experience | 11% | 12% |
On the basis of the numbers mentioned above, Tadalafil outshines as a preferred choice among men to treat Erectile Dysfunction compared to Sildenafil.
Tadalafil vs Sildenafil: How to choose?
Here’s a table that can help you choose the best ED medication in accordance with your preferences:
Aspects | Tadalafil | Sildenafil |
Quicker onset of action | ✅ | |
Lasts longer | ✅ | |
More dosage formulations | ✅ | |
Lesser adverse side effects | ✅ | |
Available over-the-counter | ✅ | |
Lesser interactions | ✅ | |
Better ratings & reviews | ✅ |
Conclusion
When deciding between Tadalafil and Sildenafil for treating Erectile Dysfunction, it’s essential to consider your specific needs and preferences. Tadalafil, known for its longer duration of action and lower risk of vision-related side effects, offers increased flexibility in intimacy.
On the other hand, Sildenafil provides more dosage options and a quicker onset of action, making it ideal for spontaneous encounters. Consult with your healthcare provider to determine which medication aligns best with your health profile and lifestyle. Remember, both drugs have proven efficacy in improving erectile function, offering hope and relief for those seeking effective ED treatment.
Frequently Asked Questions
What is the risk of vision side effects with Sildenafil vs Tadalafil?
Sildenafil carries a slightly higher risk of causing vision changes, such as blue-tinted or blurred vision, compared to Tadalafil. Consult your doctor to determine the safest option based on your individual health and preferences.
Which medicine is safer to treat ED, Tadalafil or Sildenafil?
Both Tadalafil and Sildenafil are generally safe for treating ED. Always consult a healthcare provider to discuss the most suitable option for your health, as both medicines have certain side effects.
Can I take Tadalafil 20mg daily?
Taking Tadalafil 20mg daily is not recommended unless specifically prescribed by a healthcare provider, as their effects may extend beyond 24 hours. For daily use, a lower dose of Tadalafil is typically recommended. Consult your doctor to determine the appropriate dosage and frequency for your individual needs.
Which ED medicine lasts the longest?
Tadalafil (brand name Cialis) typically lasts the longest among ED medicines, with effects lasting up to 36 hours after dosing. This longer duration of action provides increased flexibility compared to other ED medications like Sildenafil (brand name Viagra).
Tadalafil 20 mg vs Sildenafil 100mg, which one is more effective?
Tadalafil 20mg and Sildenafil 100mg are both effective for treating ED. Tadalafil’s longer duration of action (up to 36 hours) may offer more sustained efficacy compared to Sildenafil’s shorter duration (up to 4 hours), but individual responses can vary.
