Peyronie’s Disease and Viagra: Insights for Safe Experience 

Shilpi Jain
Medically reviewed by
Dr. Kaushal

Review medical content on WOW Rx Pharmacy, so that accurate drug use information is easily accessible to everybody.
Dr. Akansha is a licensed Clinical Pharmacologist. She possesses remarkable knowledge in Pharmacovigilance, prescription analysis, drug information, and drug safety services. Additionally, she is a keen learner and an educator.

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peyronie's disease and viagra

If you’re dealing with Peyronie’s disease, a condition also known as a curved or bent penis, you may have explored various remedies in search of an effective solution. 

One potential treatment that has been discussed for its possible benefits is Viagra, the well-known “little blue pill”.

However, studying the disease and the drugs one uses is an important criterion in addressing the problem and finding suitable treatment options. 

This article will examine the interaction of  Peyronie’s Disease and Viagra and if it can serve as a viable treatment for individuals with Peyronie’s Disease.

Is it safe for men with Peyronie’s disease to take Viagra?

So, is Peyronie’s disease and Viagra a good-to-go combination deal?

Peyronie’s disease and Viagra combination use Viagra as a potential solution for Peyronie’s disease. 

Peyronie’s disease is characterized by developing fibrous plaques or lumps within the penile tissue.

The main symptom of Peyronie’s disease is the bending of the penis during erection. 

This bending can range from mild to severe and may be associated with pain or difficulties achieving and maintaining an erection.

While the exact causes of Peyronie’s disease are not fully understood, there is some association with trauma to penile tissues, genetic factors, and pre-existing conditions such as Erectile Dysfunction. 

Viagra is widely prescribed for treating Erectile Dysfunction.

It falls into the category of Phosphodiesterase type 5 inhibitors, whose primary function is to increase blood flow to the penis.

Now, let’s explore how Viagra might assist in managing this condition.

Peyronie’s Disease and Viagra Safety

Research indicates that using Viagra is unlikely to exacerbate Peyronie’s disease or harm the penis during sexual activity. 

However, it’s always prudent to exercise caution if you have concerns.

Nevertheless, Viagra has demonstrated potential in relieving Erectile Dysfunction (ED) and mild curvature in individuals with early-stage Peyronie’s disease. 

There is no conclusive evidence supporting the idea that Viagra therapy can effectively manage or cure Peyronie’s disease.

Fact:
Peyronie’s disease is indeed a relatively common condition that can affect men. The statistics such as it affecting 9% of men and one in 11 men presenting with Peyronie’s disease in their lifetime, highlight the prevalence of this condition.

How does Viagra help Peyronie’s disease

Blue pills for mens healthSource: Iurii_Maksymiv
Viagra pills

Sildenafil citrate, the active ingredient in Viagra, works by promoting blood flow to penis resulting in the relaxation of smooth muscle cells and tissues.

This gives penis the desired erection. 

To get a bit technical, Sildenafil inhibits Phosphodiesterase 5 (PDE-5), which breaks down cGMP, allowing the blood vessel walls within the penis wall to relax.

Function of cGMP

cGMP is the intracellular trigger of penile erection. The action of cGMP leads to the release of calcium from the intra-cellular tissues in smooth muscles surrounding the penis. This results in the relaxation of the blood vessels, increasing blood flow to the penis. 

So, if erections depend on good blood flow, it might seem that Viagra, by facilitating vasodilation and improved blood flow, could also be beneficial for Peyronie’s disease.

However, the situation isn’t necessarily that simple. Let’s take a closer look.

In the short term, when Viagra is taken traditionally for Erectile Dysfunction, it can indeed have an almost immediate effect on erections, typically lasting for about 4 hours.

This is because the medication helps relax the smooth muscle tissues within the penis and promotes increased blood flow resulting in a firmer and more reliable erection.

However, since Peyronie’s disease operates differently, there’s no guarantee that Viagra will yield similar results, especially when considering long-term effects.

Let’s move on to the studies regarding the use of Viagra among Peyronie’s disease patients to understand this better.

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Studies about Peyronie’s disease and Viagra

The question is whether Viagra is effective in treating Peyronie’s disease.

Well, it’s a bit of a mixed bag. 

While there is limited data on the specific efficacy of Sildenafil (Viagra) in addressing penile curvature, some studies suggest potential benefits in managing specific symptoms.

In one study conducted, patients were given a combination of Tadalafil (another PDE5 inhibitor) and Pentoxifylline (an anti-inflammatory agent), while another group received a placebo with Pentoxifylline as treatment control. 

After a six-month trial period, at least a mean percentage decrease in curvature and an improvement in Erectile Dysfunction was observed in the Tadalafil group.

In light of these findings, it’s important to note that achieving complete penile curvature normalization through ED medications like Viagra is not something you can rely on with certainty.

One should definitely think of the side effects of these medications.

Side effects of Viagra for Peyronie’s disease

Headache - side effectSource: SIphotography_from_Getty_Images
Headache – side effect

When contemplating the use of Viagra to address Peyronie’s disease, it’s crucial to be mindful of the possible side effects that could arise.

Common side effects often linked to the use of Viagra include:

  • Headache
  • Dizziness
  • Upset stomach
  • Redness in the face, neck, or chest; Flushing
  • Acid reflux or indigestion
Warning:
It’s essential to note that it is recommended not to combine ED medications like Viagra with Alpha-blockers or Nitrates, as this combination may potentially lead to life-threatening hypotension.

Proven treatments for Peyronie’s disease

Several treatments are available for Peyronie’s disease, each with its advantages and potential side effects. Here’s a discussion of some proven treatments:

Surgery

Surgery is generally not recommended until Peyronie’s disease has stabilized and no longer progresses.

Doctors consider the disease’s progression, plaque quantity, and curvature severity to select the most suitable surgical technique. 

Ultrasound can help determine the plaque’s precise location. Surgery, while effective, carries inherent risks, and the chosen procedure may worsen Peyronie’s symptoms.

Shockwave Therapy

In addition to invasive treatments like surgery, non-invasive shockwave therapy is an option

This treatment uses low sound waves to break up the plaque in the penis, reversing the effects of Peyronie’s disease.

Shockwave therapy can reduce the curvature, pain, and ED associated with Peyronie’s disease.

Some treatments, particularly penis implantation and shockwave therapy, may potentially treat or cure ED. 

Final Words

Viagra may have limited potential in addressing specific symptoms associated with Peyronie’s disease, particularly in relieving mild curvature and ED.

However, it is not a proven or guaranteed treatment for the condition.

No conclusive evidence supports the idea that Viagra can effectively manage or treat  Peyronie’s disease.

It’s vital to consider the potential benefits against the possible side effects and risks associated with medication use. 

Proven treatments for Peyronie’s disease include surgical options, such as grafting, plication, and implantation, which can effectively reduce penile curvature. 

However, treatment choices should be tailored to an individual’s specific condition and needs, and consultation with a healthcare professional is essential.

Frequently Asked Questions

Can I take Viagra if I have Peyronie’s disease?

Individuals can generally take Viagra (Sildenafil) with Peyronie’s disease, as it is unlikely to exacerbate the condition or harm the penis during sexual activity. Viagra may help alleviate the symptoms of Erectile Dysfunction that often accompany Peyronie’s disease, such as difficulty achieving or maintaining an erection.

Can Viagra cause Peyronie’s disease?

Peyronie’s disease is primarily characterized by the development of fibrous plaques or lumps in the penile tissue, often resulting from penile trauma, or other pre-existing conditions. Viagra, when used as prescribed, is a medication designed to treat Erectile Dysfunction by improving blood flow to the penis, and it does not directly cause Peyronie’s disease.

Can Peyronie’s disease cause Erectile Dysfunction?

Yes, Peyronie’s disease can cause Erectile Dysfunction (ED) in some cases. The development of fibrous plaques or scar tissue in the penile tissue can lead to curvature or bending of the penis during an erection. Peyronie’s disease-related curvature, pain, and psychological distress can contribute to ED.

How do you treat Peyronie’s Erectile Dysfunction?

The treatment of Erectile Dysfunction associated with Peyronie’s disease often involves addressing both conditions simultaneously. Common approaches to managing Peyronie’s Erectile Dysfunction include drugs like Viagra (Sildenafil), Cialis (Tadalafil), or Levitra (Vardenafil).

Citations:
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