A Closer Look: Is Sildenafil Safe for You
Besides being used for Erectile Dysfunction, Sildenafil has many uses because of its unique properties.
However, there is a growing need to know how Sildenafil can adversely affect individuals who take it for ED.
The question, “Is Sildenafil safe?” concerns people suffering from ED and patients with other ailments like cardiovascular problems.
To judge the safety of Sildenafil, one must evaluate the side effects, uses, and contraindications of Sildenafil.
Read on to learn more about the safety considerations of Sildenafil use.
Sildenafil uses
Sildenafil is primarily used to treat men with Erectile Dysfunction.
Being a Phosphodiesterase 5 inhibitor (PDE5), Sildenafil functions to drop calcium levels in the smooth muscles and enables relaxation.
In a flaccid penis, the smooth muscles stay contracted due to the presence of the enzyme PDE-5.
More blood flow in the penis results in smooth muscle relaxation leading to an erection.
Owing to PDE-5 inhibition, Sildenafil can cause a spontaneous erection in men with ED.
Side effects of Sildenafil
Sildenafil, like any other medication, is not without its side effects, which need to be known beforehand to ascertain the safety of Sildenafil.
A study done to assess the different side effects of Sildenafil found the following symptoms:
- Flushing
- Headache
- Nasal congestion
- Heartburn
However, most of these symptoms were mild and swiftly subsided once the medication was stopped.
Additionally, no associations were found between higher doses and the severity of side effects.
In rare conditions, psychosis can occur due to side effects of Sildenafil.
Sildenafil also has the following effects on the vision of the patients:
- Blurry vision
- Light sensitivity
- Keratitis (inflammation of the cornea)
- Conjunctival hyperemia (inflammation of blood vessels of the conjunctiva)
- Increased Intraocular Pressure (IOP)
Serious side effects, like central serous retinopathy and serous macular detachment, can also occur.
Sildenafil contraindications
Contraindications refer to a specific situation that is unsuitable for using the given drug to the person as it can cause adverse effects.
The contraindications for Sildenafil are as follows:
- Sildenafil is contraindicated with the coadministration of nitrates since the two drugs can synergistically react to cause life-threateningly low blood pressures
- Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) and more retinal disorders are contraindicated to the use of Sildenafil
- Sildenafil is contraindicated in patients with Parkinson’s disease or multiple system atrophy as it may increase Hypotension symptoms
- Patients with Sickle Cell Anemia are contraindicated as Sildenafil can cause Priapism (long and painful erection)
Is Sildenafil safe
The side effects and contraindications of Sildenafil show that there are a large number of adverse possibilities that must be considered to use it safely.
However, these effects are either mild or extremely rare and do not happen under normal dosages and conditions.
Research has shown that Sildenafil has considerable potential in treating ED without adverse effects in most patients.
The participants in the research were found to have good tolerability for the drug and developed either mild side effects or nothing at all.
It is important to know that Sildenafil is a prescription drug under FDA regulations and needs the recommendation of a qualified doctor before use.
Concerns about “Is it safe to take Sildenafil daily?” are valid but improbable if proper medical instructions are followed.
Following the instructions that come with the medication and the doctor’s advice is mandatory for the safe use of Sildenafil.
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Sildenafil primarily inhibits the activity of the PDE-5 enzyme, which results in a sustained erection.
Side effects of Sildenafil include headache, heartburn, keratitis, and conjunctival hyperemia, among many others.
Most of these side effects are either mild and disappear with the discontinuation of the medication or are rare adverse effects.
Sildenafil is contraindicated in people with cardiovascular issues, Parkinson’s disease, and Sickle Cell Anemia.
Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) and psychosis are some rare conditions that can occur with taking Sildenafil.
The side effects and contraindications have little effect on the safety of Sildenafil if all the instructions are followed.
For safety concerns, it is advised always to seek professional advice before taking Sildenafil.
Frequently Asked Questions
Is Sildenafil harmful to health?
Sildenafil is not harmful to human health if taken with proper precautions and for a limited time. Most health effects of Sildenafil are associated with contraindicated persons or improper dosage administrations. If side effects do occur, most are mild and subside when the treatment is withdrawn.
Is Sildenafil safe for the heart?
Sildenafil is safe for people with a healthy heart. However, it is contraindicated in people with cardiovascular problems and can cause life-threatening complications like extremely low blood pressure, especially if the patient takes nitrate medications.
Is Sildenafil safe to take daily?
Sildenafil can be taken daily but only once per day for all doses. Most doses are usually 50 mg daily, but other 25 mg and 100 mg variations are also commercially available. However, the more often you take Sildenafil, the more exposed you become to the side effects of Sildenafil, too.
Who should avoid Sildenafil?
Persons with cardiovascular problems who take nitrate medications, people with vision problems, Parkinson’s disease or multiple system atrophy, and Sickle Cell Anemia should avoid taking Sildenafil at all costs. If there is a need to take Sildenafil, a consultation with the doctor is mandatory before taking Sildenafil.
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