Estrogen Blockers for Bodybuilding: Understanding Their Role and Implications

Amoha Jha
Medically reviewed by
Dr. Kaushal

Review medical content on WOW Rx Pharmacy, so that accurate drug use information is easily accessible to everybody.
Dr. Akansha is a licensed Clinical Pharmacologist. She possesses remarkable knowledge in Pharmacovigilance, prescription analysis, drug information, and drug safety services. Additionally, she is a keen learner and an educator.

Last Updated:

estrogen blocker bodybuilding

The pursuit of bodybuilding with the goals of optimal muscle growth, fat loss, and performance enhancement has led to the exploration of various strategies and supplements.  

One such thing that has gained attention is using Estrogen blockers for bodybuilding. 

It is often referred to as Selective Estrogen Receptor Modulators (SERMs), which are used to block Estrogen in the body.

Also, Aromatase Inhibitors (AIs) are designed to regulate and reduce the levels of Estrogen in the body. 

However, the use of Estrogen blockers in bodybuilding is a complex and controversial topic that requires careful consideration of the potential benefits and risks.

Continue reading this article to learn more about Estrogen blockers for bodybuilding.

Why do bodybuilders take Estrogen blockers

Bodybuilders may use Estrogen blockers alongside Anabolic steroid intake for specific reasons related to optimizing muscle growth and minimizing undesirable side effects.

Anabolic steroids, often used to enhance muscle development, can lead to elevated levels of Testosterone.

This hormone can subsequently convert into Estrogen. 

Good to know:
In men, Estrogen is produced in smaller amounts but still contributes to maintaining bone density and modulating mood.

Due to this conversion, the Estrogen levels in males increase.

High levels of Estrogen can potentially lead to increased fat storage, water retention, and in some cases, Gynecomastia (the development of breast tissue in males).

Other side effects of high Estrogen include Erectile Dysfunction, infertility, etc.

Estrogen blockers (such as AIs) serve to decrease these Estrogen-related effects by inhibiting the enzyme Aromatase, which converts Testosterone into Estrogen. 

Another form of Estrogen blocker, which is SERM, binds to the Estrogen receptor and reduces Estrogen levels.

Thus, to continue the use of Anabolic steroids while reducing the side effects, bodybuilders take the route of Estrogen blockers.

What does blocking Estrogen do to your body

By reducing Estrogen levels, bodybuilders aim to achieve several potential benefits:

Reduced water retention

High Estrogen levels can lead to water retention, giving a bloated appearance. 

Lowering Estrogen could help achieve a leaner, more defined physique.

Minimized fat accumulation

Estrogen can contribute to fat storage, particularly in certain areas like the hips and thighs. 

Lowering Estrogen might help control fat accumulation.

Prevention of Gynecomastia

Excess Estrogen can lead to Gynecomastia in some individuals. 

Estrogen blockers are sometimes used to decrease this risk.

Reduced effect on fertility

Estrogens have a prominent effect on male fertility.

When the levels of this hormone are increased, it can cause infertility in males.

Here, Estrogen blockers can help reduce this risk.

Maintain erectile function

When there is an increase in Estrogen levels in the body of males, it can impact their erectile function.

Estrogen blockers for bodybuilding can reduce the risk of Erectile dysfunction.

Reduced risk of Depression

Studies have shown that higher levels of Estrogen can lead to symptoms of Depression.

When bodybuilders use Estrogen blockers, it may affect reducing these Estrogen-induced Depression symptoms.

Checkout Cart:
You can buy Aristu Anastrozole, a prescription medication from WowRxPharmacy, at an affordable price.

Controversies and risks

While the potential benefits of Estrogen blockers in bodybuilding are often discussed, it’s crucial to recognize the potential risks and uncertainties associated with their use:

Hormonal imbalance

By inhibiting Estrogen production, users risk disrupting the delicate balance between Estrogen and Testosterone. 

This imbalance could lead to unwanted side effects and health issues.

Bone health

Elbow bones injurySource: horillaz_from_Getty_Images
Elbow bones injury

Estrogen is essential for maintaining bone health in males. 

Over-suppression of Estrogen might negatively impact bone health, leading to increased fracture risk.

Cardiovascular effects

Estrogen plays a role in cardiovascular health.

Its drastic reduction due to Estrogen blockers could potentially have negative implications for heart health.

Balancing risk and reward

The use of Estrogen blockers in bodybuilding is not a decision to be taken lightly. 

Prior to considering their use, individuals should consult with a qualified healthcare professional, preferably one experienced in sports medicine or endocrinology. 

These professionals can provide personalized advice, assess potential risks, and monitor hormonal levels to ensure overall well-being.

It’s essential to approach bodybuilding and fitness goals with a holistic perspective that prioritizes health and sustainability. 

While Estrogen blockers might offer some short-term advantages, the potential long-term risks must be carefully weighed against the desire for immediate results. 

Achieving success in bodybuilding should not come at the expense of overall health and hormonal balance.

Never take Estrogen blockers without a prescription. If a pharmacy sells Estrogen blockers as an OTC medication, report it to the regulatory authorities.


In the quest for muscle growth and performance enhancement, the consideration of Estrogen blockers for bodybuilding has surfaced as a significant topic. 

Estrogen, while vital for various bodily functions, can lead to undesirable effects when its levels rise due to anabolic steroid use. 

Estrogen blockers, including Aromatase Inhibitors (AIs) and Selective Estrogen Receptor Modulators (SERMs), emerge as potential solutions to mitigate these effects. 

By curbing water retention, fat accumulation, Gynecomastia risk, fertility challenges, and Depression symptoms, Estrogen blockers present compelling short-term benefits. 

However, the path of using these agents demands caution, with potential risks such as hormonal imbalances, compromised bone health, and cardiovascular concerns. 

Aspiring bodybuilders must consult healthcare professionals to navigate the crucial balance between immediate gains and enduring health. 

The pursuit of physical excellence should harmonize with well-being, recognizing that true success is achieved by upholding holistic health. 

Frequently Asked Questions

How does the human body deteriorate when all Estrogen is blocked?

When all Estrogen is blocked in the human body, many effects occur. Bone health is compromised, increasing fracture risk. Cardiovascular health may decline due to Estrogen’s role. Hormonal balance falters, potentially leading to adverse side effects. Balanced Estrogen levels are crucial for overall well-being and maintaining physiological harmony.

What happens when you block the Estrogen in the body?

Blocking Estrogen in the body, often done with Estrogen blockers like Aromatase Inhibitors (AIs) or Selective Estrogen Receptor Modulators (SERMs), can lead to reduced water retention, minimized fat accumulation, lowered Gynecomastia risk, improved fertility, reduced risk of Erectile dysfunction, and potentially alleviating Estrogen-induced Depression symptoms.

What do bodybuilders take to block Estrogen?

Bodybuilders often block Estrogen by using Aromatase Inhibitors (AIs) and Selective Estrogen Receptor Modulators (SERMs). AIs inhibit the conversion of Testosterone into Estrogen, while SERMs bind to Estrogen receptors, reducing Estrogen’s effects. This helps minimize Estrogen-related side effects, such as fat accumulation and can improve muscle definition during Anabolic steroid use.

What happens if a man takes Estrogen blockers?

When a man takes Estrogen blockers like Aromatase Inhibitors (AIs) or Selective Estrogen Receptor Modulators (SERMs), it can lead to decreased Estrogen levels. This can result in reduced water retention, minimized fat accumulation, lowered risk of Gynecomastia, improved fertility, and potential improvement in related issues like Erectile Dysfunction. 

uses only high-quality sources while writing our articles. Please read our content information policy to know more about how we keep our content reliable and trustworthy.

More Articles Like This

Leave a Comment

Receive the latest articles in your inbox!