Nulastin vs Latisse: Which One Grows Better Lashes?

Amisha Jain
Medically reviewed by
Dr. Kaushal

Review medical content on WOW Rx Pharmacy, so that accurate drug use information is easily accessible to everybody.
Dr. Akansha is a licensed Clinical Pharmacologist. She possesses remarkable knowledge in Pharmacovigilance, prescription analysis, drug information, and drug safety services. Additionally, she is a keen learner and an educator.

Last Updated:

Nulastin vs Latisse: Which one is Better?

We all admire long, fluttery eyelashes, but not everyone is naturally blessed with them. For those suffering from Hypotrichosis of the eyelashes, inadequate lash growth can significantly impact their self-confidence. 

While Hypotrichosis Simplex is rare, affecting fewer than 1000 people in the US, conditions like Cancer and Alopecia can also lead to Hypotrichosis. To address this, products like Nulastin and Latisse are used as eyelash growth serums.

This article explores the differences between Nulastin vs Latisse, helping you make an informed decision, so keep on reading.

Quick review

Studies have not been conducted that directly compare the efficacy of Nulastin and Latisse.

But a review by Bishr Al Dabagh and Julie Woodward promotes Bimatoprost (present in Latisse) as an eyelash-enhancing product. Another research by Wirta D et al. has shown considerable lash growth in cancer patients post-chemotherapy with Bimatoprost use.

UsesIt is used to lengthen, darken, and thicken eyelashes.It is prescribed to lengthen, darken, and thicken eyelashes.
FDA status in the yearSince it is a cosmetic product, not a medication, it doesn’t require FDA approval.2008
Active ingredientsElastatropin, SymPeptide, Keracyte, Phosphate Buffered SalineBimatoprost
Avg. Cost per 3ml$79 (approx.)$120-$150 (approx.)

What is Nulastin?

eyes of a woman
Woman with enhanced eye lashes

Nulastin is a cosmetic product used to revitalize lashes, brows, skin, and hair. It is not a medication, so it does not require FDA approval. Nulastin has active ingredients such as Elastatropin, SymPeptide, Keracyte, and Phosphate-Buffered Saline. These are synthetic compounds designed to enhance skin and hair health.

It aims to address the hair in the anagen (growth/active phase) and late telogen (resting/shedding phase) phases. Nulastin nourishes the cells that play a part in producing hair follicles. It is not recommended for anyone below the age of 18. Additionally, it is advised not to use it if you are pregnant or breastfeeding.

What is Latisse?

Latisse is an FDA-approved, prescription-based medication for Hypotrichosis. It works by prolonging the duration of the eyelash growth cycle. Its active salt is Bimatoprost, which belongs to a class of medications called Prostaglandin Analogs. Topical Bimatoprost in a concentration of 0.03% is used as an eyelash growth serum. It promotes the growth of thicker, longer, and darker lashes.

Originally developed as a prescription eye drop called Lumigan for treating Glaucoma, Latisse was discovered to have an unexpected side effect: thicker and longer eyelashes.

Studies have even proven the safety and efficacy of Bimatoprost in pediatric patients suffering from Hypotrichosis. However, it is not advisable to use it for those under 18 without medical advice. Though Latisse is not approved for use on eyebrows, doctors might sometimes recommend it for off-label use. A study published in NCBI has shown the efficacy of Bimatoprost in improving eyebrow growth.

Pros and Cons

Here is a general overview of the pros and cons of Nulastin vs. Latisse, which might be useful.

Can be used on lashes as well as eyebrows
Effectively treat HypotrichosisOff-label use for eyebrow growth could be recommended by your doctorNeeds to be applied once daily
Needs to be used twice dailyCan cause dry and itchy eyesPermanent darkening of the skin around the eyes is a side effectEffects are not permanent
Needs to be used for at least 15 minutes before applying contact lensesFDA has not approved Latisse for eyebrows

What came first: Nulastin or Latisse?

Nulastin was introduced in the market in 2016. It offers a variety of products for lash and brow growth. Latisse (0.03% Bimatoprost ophthalmic solution) was approved in 2008 for the treatment of Hypotrichosis. 

Before 2008, Bimatoprost was only used to treat Glaucoma. However, its side effect, lash growth, led to its use as a lash growth serum. Hence, between Nulastin and Latisse, Latisse has been in the market for lash growth longer than Nulastin.

Side effects

woman rubbing her eyes
Woman with itchy eyes

It is common to observe side effects from using certain medications. Some of the most frequently observed side effects of using Latisse include redness and itching of the eyes.

Other side effects include the following:

  • Burning or itching of eyes
  • Vision issues, including seeing halos around the eyes
  • Eye pain or swelling
  • Increased sensitivity to light

Nulastin, on the other hand, might show the following side effects:

  • Dry and itchy eyes
  • Permanent darkening of the periocular area
  • Change in the eye color

It is advised to get in touch with your doctor in case of any of these symptoms.

Using Nulastin or Latisse inappropriately can lead to potential side effects and risks. These may include eye irritation, dryness, redness, and even changes in eyelid skin color. It’s important to follow the instructions carefully and consult a healthcare professional if you experience any adverse effects.


It is common to see that every patient reacts to medication differently. Therefore, sharing your medical history with your doctor before starting Latisse treatment is always wise.

Bimatoprost, which is present in Latisse, may show adverse effects if you have the following conditions:

  • Renal/liver disease
  • Uveitis
  • Macular edema

However, since Nulastin is a cosmetic product, its interactions with any pre-existing conditions remain unknown. You must do a patch test before using it on the face to ensure you are not allergic to any ingredients.


When choosing between Nulastin and Latisse for eyelash growth, consider personal preferences, medical history, and desired outcomes. Nulastin offers a cosmetic approach with ingredients like Elastatropin and SymPeptide, while Latisse contains Bimatoprost, FDA-approved for Hypotrichosis.

Consult a healthcare professional to decide on the best option for you. To achieve your desired results safely, follow the recommended guidelines and monitor for adverse effects.

Frequently Asked Questions

Is Nulastin better than Latisse?

Latisse is an FDA-approved medication, while Nulastin is a cosmetic product for lash growth. Additionally, Latisse has been around for a substantially longer time than Nulastin. It is best to consult your doctor to determine the product that would work best for you.

Is Nulastin the same as Latisse?

Nulastin and Latisse are different. Nulastin is a cosmetic product, while Latisse is an FDA-approved medication for eyelash growth. They have different ingredients and hence work differently.

Is Latisse effective for eyelash growth?

Latisse is an FDA-approved medicine that promotes eyelash growth in people with Hypotrichosis. Its active ingredient is Bimatoprost. It can also be recommended for off-label eyebrow growth use.

How long does it take to see eyelash growth with Latisse?

Latisse typically takes 16 weeks to show full results, but some people may notice longer lashes after about a month. The treatment works by increasing the growth cycle of eyelash hair, and results are gradual over time.

WowRxPharmacy uses only high-quality sources while writing our articles. Please read our content information policy to know more about how we keep our content reliable and trustworthy.

More Articles Like This

Leave a Comment

Receive the latest articles in your inbox!