Estrogen Dominance Unveiled: Balancing the Hormonal Scale

Monali Sharma
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Dr. Kaushal

Review medical content on WOW Rx Pharmacy, so that accurate drug use information is easily accessible to everybody.
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estrogen dominance

Maintaining the right scales of Estrogen hormones is vital for the right state of the body.

Any deviation from normal levels, whether lower or higher, can lead to various physical and psychological complications.

A disproportionate Estrogen-Progesterone concentration, where Estrogen is on the higher side, is known as Estrogen Dominance.

It is associated with genital issues, sexual dissatisfaction, mental complications, and a risk of severe diseases, particularly those related to abnormal tissue growth.

Read on to gain insights into the causes, symptoms, and potential treatment options for addressing Estrogen Dominance. 

Symptoms associated with Estrogen Dominance

headache is a side effectSource: Iurii_Maksymiv
Headache

Dominating Estrogen can appear in a range of physical and psychological complications in the body.

The common signs of Estrogen Dominance among women may include:

  • Headaches
  • Heavy menstrual bleeding
  • Irritability and mood swings
  • Sleep disorder
  • Breast tenderness
  • Breast cyst
  • Endometriosis(lining-like tissue grows outside the uterus)
  • Fibroids(non-cancerous tissue growths in the uterus)
  • Gallbladder disease
  • Thyroid disorders

Estrogen Dominance is also associated with an elevated risk for certain severe diseases.

These may include:

  • Breast cancer
  • Ovarian cancer
  • Endometrial cancer
  • Blood clotting
  • Stroke

Estrogen plays a crucial role in male physiology as well. 

These are the common experiences associated with dominant levels of Estrogen in men:

  • Decreased sex drive
  • Poor erections
  • Infertility issue
  • Mood swings
  • Increased body fat because of metabolic dysregulation
  • Depression problem
  • Overdevelopment of breast tissue (gynecomastia) in severe cases
Information :
Low Estrogen levels too affect women adversely. The common complications include hot flashes, vaginal dryness, itchiness, discomfort during urination, and pain during sexual intercourse.

What causes Estrogen Dominance

Alcohol can result in dominance of Estrogen Source: ElenaNichizhenova_from_Getty_Images
Avoid alcohol

Several factors can contribute to the dominance of Estrogen in an individual’s body.

These factors can either increase the levels of Estrogen hormones or decrease the levels of Progesterone.

Some of these factors include:

  • An overproduction production of Estrogen by the body
  • Impaired Estrogen metabolism and secretion
  • Hormone Therapy 
  • Inflammation
  • High levels of Omega-6 fatty acids
  • Obesity
  • Hypothyroidism
  • Exposure to environmental Estrogens 
  • Stress
  • Alcohol consumption

Estrogen Dominance treatment measures

To address Estrogen Dominance, the treatment approach focuses on identifying and treating the root cause while also managing hormone levels.

Medical interventions, as well as lifestyle changes, can help curb Estrogen Dominance in the body.

Medicinal measures

Hormone Therapy and administration of Estrogen blockers are two methods commonly adopted to address Estrogen Dominance.

If Progesterone levels are low, your doctor may recommend Progesterone hormone therapy to increase them.

There are two main types of pharmaceutical Estrogen blockers: Aromatase Inhibitors (AIs) and Selective Estrogen Receptor Modulators (SERMs).

AIs, such as Anastrozole (Arimidex) and Letrozole (Femara), work by inhibiting aromatase enzymes that convert Androgens to Estrogens.

SERMs, such as Tamoxifen (Nolvadex) and Toremifene (Fareston), attach to Estrogen receptors, preventing Estrogen from binding.

It is important to note that these methods can have their own side effects and should only be adopted under the guidance of an expert.

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Alternate or natural measures

Certain natural food items have been found to have Estrogen-reducing effects on the human body.

These can be considered as aids in controlling Estrogen levels.

Some examples include:

  • Cruciferous vegetables like broccoli, cabbage, maca plant, and cauliflower have Indole-3-carbinol, which is linked to anti-estrogen activity
  • The maca plant and oyster mushrooms have the potential to block aromatase, acting as natural Aromatase Inhibitors
  • Whole soy foods can positively influence Estrogen metabolism to support controlled levels
  • Curcumin, a yellow polyphenolic pigment found in turmeric, possesses the capability to decrease Estrogen levels
  • A high-fiber diet promotes Estrogen excretion and reduces Estrogen absorption, thereby potentially blocking Estrogen activity
  • Individuals looking to curb Estrogen levels should monitor their fat intake, as high-caloric-density meals can contribute to elevated Estrogen levels
  • Consuming a vegetarian diet encourages the excretion of Estrogen in feces, resulting in serum Estrogen levels that are 15%-20% lower

Certain substances present in the environment have Estrogen-like activity.

Lowering Estrogen levels can be achieved by avoiding these elements.

  • Animal-derived products like meat, eggs, and dairy from animals treated with external hormones tend to have higher levels of Estrogen
  • Synthetic chemicals like pesticides, plastics, surfactants, and detergents, which contain Xenoestrogens, a type of Estrogen

In addition to dietary measures, certain lifestyle choices can also help reduce Estrogen levels:

  • Avoiding alcohol can be advantageous, as it can hinder the detoxification of Estrogen and result in higher levels of Estradiol
  • Exercise and weight loss should be encouraged as they contribute to balanced Estrogen levels in the body
  • Managing stress through relaxation exercises and mind-body practices can help maintain a healthy Estrogen-to-Progesterone ratio
Warning:
Aromatase Inhibitors are linked to several side effects, with the most common being the development of joint pain (Arthralgias). Hence medical supervision is recommended for their use.

Summary

Estrogen Dominance means higher than usual Estrogen relative to the Progesterones, which environmental factors, diet, stress, and medications can cause.

The common signs of Estrogen Dominance among women may include headaches, menstrual bleeding, disturbed mood and sleep, breast tenderness, and abnormal tissue growth.

Estrogen Dominance is also associated with an elevated risk for certain severe diseases, breast, ovarian, and endometrial cancers, blood clotting, and stroke.

Estrogen Dominance can cause decreased sex drive, poor erections, and abnormal breast tissue in men.

Hormone therapy and Estrogen blockers such as Aromatase Inhibitors and SERMs are the medical treatment approaches to curb Estrogen Dominance.

Cruciferous vegetables like broccoli and cabbage, oyster mushrooms, turmeric, soy foods, and a diet high in fiber and low in calories can reduce Estrogen.

In addition to dietary changes, lifestyle interventions such as regular exercise, avoiding alcohol, and managing weight and stress can also control the Estrogen to Progesterone ratio.

It is important to note that the effectiveness of these medications and methods can vary from person to person, and not all approaches may suit everyone.

Frequently Asked Questions

What is Estrogen Dominance?

Estrogen Dominance occurs when there is excessive Estrogen compared to Progesterone hormones in the body. This imbalance can be caused by factors like hormonal imbalances, environmental influences, or certain medical conditions. Common symptoms may include headaches, weight increase, disturbed mood and sleep, and irregular menstrual cycles.

What does Estrogen Dominance mean?

Estrogen dominance refers to a hormonal imbalance where there’s an excess of Estrogen relative to other hormones in the body, potentially leading to various health issues such as irregular periods, mood changes, and increased risk of certain conditions.

How to decrease Estrogen Dominance?

Hormone therapy and medications like Aromatase Inhibitors and SERMs are used to treat Estrogen Dominance. Additionally, maintaining a healthy weight, regular physical activity, and managing stress levels can also help. Moreover, adopting a diet that includes vegetables, fiber, cruciferous vegetables, and omega-3 fatty acids can support hormonal equilibrium.

What are the signs of Estrogen Dominance?

Estrogen Dominance appears as weight gain, bloating, breast sensitivity, mood fluctuations, irregular periods, reduced libido, and fatigue. Additional potential symptoms include headaches, sleeplessness, and abnormal tissue growth in the breast and uterus. The symptoms among men may include decreased sex drive, poor erections, mood swings, and overdevelopment of breast tissue (Gynecomastia).

Citations:
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