Estrogen Blocker for Women: Benefits, Natural Options, and Considerations

Sourav Gupta
Medically reviewed by
Dr. Kaushal

Review medical content on WOW Rx Pharmacy, so that accurate drug use information is easily accessible to everybody.
Dr. Akansha is a licensed Clinical Pharmacologist. She possesses remarkable knowledge in Pharmacovigilance, prescription analysis, drug information, and drug safety services. Additionally, she is a keen learner and an educator.

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estrogen blocker for women

Estrogen, a vital hormone in the female body, plays a significant role in regulating various bodily functions. 

However, an excess of Estrogen can lead to certain health issues. 

This is where Estrogen blockers come into play.

Estrogen blockers help reduce the amount of Estrogen in the body by stopping Estrogen from being produced altogether.

In this article, we will explore the benefits, natural options, and considerations for Estrogen blocker for women.

What are Estrogen blockers

Estrogen blockers, also known as Aromatase Inhibitors, are substances that help regulate Estrogen levels by inhibiting the activity of the Aromatase enzyme. 

This enzyme converts Androgens into Estrogen. 

By blocking this process, Estrogen blockers can effectively reduce Estrogen levels in the body. 

They are commonly used to treat conditions such as Breast Cancer and hormonal imbalances.

Fact:
Estrogen blockers suppress the production of Estrogen by inhibiting the enzyme Aromatase and reducing Estrogen levels.

By reducing Estrogen levels, these Inhibitors are commonly used in treating Hormone-Sensitive Breast Cancer and postmenopausal women.

Aromatase Inhibitors: Pharmaceutical Estrogen blockers

Aromatase Inhibitors are medications that work by blocking Aromatase from converting other hormones to Estrogen.

Some of the common Aromatase Inhibitors are as follows:

Letrozole

Letrozole is an Aromatase inhibitor commonly used to treat postmenopausal women with Hormone Receptor-Positive Breast Cancer. 

It works by reducing Estrogen production in the body, thereby slowing down the growth of cancer cells that rely on Estrogen.

Anastrozole

Anastrozole is another Aromatase inhibitor used in Breast Cancer treatment. 

It functions similarly to Letrozole by inhibiting Estrogen synthesis.

Exemestane

Exemestane is prescribed to postmenopausal women with Breast Cancer. 

It functions by irreversibly binding to Aromatase enzymes, effectively blocking Estrogen production.

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Natural Estrogen blocker for women

Flaxseed's influence on Estrogen balance is subtleSource: eliane from Getty Images Signature
Flaxseed

Apart from the medications that can help in blocking Estrogen, various seeds, and vegetables can also help.

Following are some of the natural Estrogen blocker for women:

  • Cruciferous vegetables: Foods like broccoli, cauliflower, and kale contain compounds that promote the metabolism of Estrogen, helping to balance hormone levels
  • Flaxseeds: Rich in lignans, flaxseeds can bind to Estrogen receptors and potentially reduce the effects of excess Estrogen
  • Chasteberry: Also known as Vitex, chasteberry can help regulate hormonal imbalances by affecting the hypothalamus and pituitary glands
  • Turmeric: Curcumin, the active compound in turmeric, has anti-inflammatory properties and may help in Estrogen metabolism
  • Green tea: Epigallocatechin Gallate (EGCG) in green tea can potentially inhibit Aromatase activity and reduce Estrogen levels

Benefits of Estrogen blockers for women

Estrogen blockers have various benefits for women, from preventing Breast Cancer to hormonal imbalance.

These are some of the benefits you can get after taking Estrogen blockers:

Breast cancer prevention

Estrogen blockers for Breast cancer treatmentSource: Rido
Breast cancer prevention

Estrogen blockers are often prescribed as part of Breast Cancer treatment plans. 

They work by reducing Estrogen levels, which can help prevent the growth of Estrogen-sensitive tumors.

Hormonal imbalance

Women experiencing hormonal imbalances, such as Estrogen dominance, can benefit from Estrogen blockers. 

These blockers can help restore balance and alleviate symptoms of Estrogen dominance like irregular periods, mood swings, and bloating.

Weight management

Estrogen dominance has been linked to weight gain, particularly around the abdomen. 

By using Estrogen blockers, women may experience improved weight management.

Potential side effects of medications

While pharmaceutical Estrogen blockers can be highly effective, they come with their own set of considerations and potential side effects:

  • Menopausal symptoms: Similar to natural Estrogen blockers, pharmaceutical options can lead to menopausal symptoms such as hot flashes, night sweats, and vaginal dryness
  • Bone health: Prolonged use of Aromatase Inhibitors can reduce bone mineral density, increasing the risk of fractures. Regular bone health assessments are recommended for women on these medications
  • Cardiovascular health: Some studies suggest a potential link between Aromatase Inhibitors and an increased risk of cardiovascular issues. Although, further research is needed to understand this relationship fully
  • Fertility concerns: Aromatase Inhibitors can impact fertility, making them unsuitable for women who plan to conceive
  • Drug interactions: These medications may interact with other drugs, affecting their efficacy or causing adverse effects. It’s crucial to inform your healthcare provider of any other medications you are taking
Warning:
Consult your doctor if you face any side effects. If left untreated, these may lead to severe complications.

Conclusion

Estrogen blockers offer a multifaceted approach to maintaining women’s health by regulating Estrogen levels. 

They can help prevent the growth of certain kinds of Breast Cancer, hormone imbalances, keeping bones strong, and even managing weight. 

But, just like with anything, there are things to think about, such as possible side effects and talking to a doctor before using them. 

Whether it’s natural choices or medicines, Estrogen blockers can be good for women’s health when used wisely.

The right balance between managing Estrogen levels and maintaining overall health is key to reaping the benefits while minimizing side effects.

Frequently Asked Questions

What is a prescription Estrogen blocker for females?

Anastrozole is a prescription Estrogen blocker for females. It’s used to treat Breast Cancer by inhibiting Estrogen production. Moreover, it helps prevent the growth of Estrogen-sensitive tumors.

What happens if a woman takes Estrogen blockers?

When a woman takes Estrogen blockers, these regulate Estrogen levels by inhibiting the activity of the Aromatase enzyme. This can lead to reduced Estrogen production, which is used in medical treatments to address conditions such as Breast Cancer and hormonal imbalances.

What are the side effects of blocking Estrogen?

Blocking Estrogen can lead to side effects like menopausal symptoms (hot flashes, night sweats, vaginal dryness). This can cause a potential impact on bone health and fertility, and cardiovascular issues. It’s essential to consider these effects and consult a healthcare provider when using Estrogen blockers.

What is a natural Estrogen blocker?

Cruciferous vegetables (broccoli and cauliflower), as well as flaxseeds, turmeric, and green tea, are natural Estrogen blockers. These foods contain compounds that can help balance hormone levels and promote healthy Estrogen metabolism in the body.

Citations:
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