{"id":20440,"date":"2023-11-01T08:44:02","date_gmt":"2023-11-01T12:44:02","guid":{"rendered":"https:\/\/wowrxpharmacy.com\/blog\/uncategorized\/causes-of-alopecia-areata\/"},"modified":"2024-07-31T03:28:02","modified_gmt":"2024-07-31T07:28:02","slug":"causes-of-alopecia-areata","status":"publish","type":"post","link":"https:\/\/wowrxpharmacy.com\/es_co\/blog\/caida-del-cabello\/causes-of-alopecia-areata\/","title":{"rendered":"Uncovering the Causes of Alopecia Areata"},"content":{"rendered":"<p>Alopecia Areata is an autoimmune disorder that causes hair loss in patches.&nbsp;<\/p>\n\n\n\n<p>Hair loss is due to an immune system attack on the hair follicles.&nbsp;<\/p>\n\n\n\n<p>A study by Fricke and Miteva has shown that 2% of Areata affects 2% of the worldwide population.&nbsp;<\/p>\n\n\n\n<p>En <a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/causes-of-alopecia\/\" target=\"_blank\" rel=\"noopener\" title=\"causes of Alopecia\" data-wpil-keyword-link=\"linked\">causes of Alopecia<\/a> Areata are complex and still under research.&nbsp;<\/p>\n\n\n\n<p>Experts claim that a combination of genetic, environmental, and dietary factors triggers hair fall.<\/p>\n\n\n\n<p>But, the immune response does not damage the hair follicles, and hair can regrow on treatment.&nbsp;<\/p>\n\n\n\n<p>Continue reading to know more about the causes and risk factors that can lead to <a href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/alopecia-areata\/\" target=\"_blank\" rel=\"noreferrer noopener\">Alopecia Areata<\/a>.&nbsp;<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"genesnbsp\">Genes <\/h2>\n\n\n<p>Areata is an autoimmune disorder that generally runs in families, says a study by Simkaou, Butcher, et al.<\/p>\n\n\n\n<p>It is a <a href=\"https:\/\/www.naaf.org\/alopecia-areata\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">polygenic disease<\/a> caused due to interactions of more than one gene.&nbsp;<\/p>\n\n\n\n<p>Genetic perspectives of Areata are studied by Biran et al.&nbsp;<\/p>\n\n\n\n<p>En <a href=\"https:\/\/www.jdsjournal.com\/article\/S0923-1811(15)00006-7\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">estudiar<\/a> stated that genes responsible for Areata belong to the family called Human Leukocytes Antigens (HLAs).&nbsp;<\/p>\n\n\n\n<p>The HLA complex works to help the immune system distinguish the bodies from proteins made by foreign bodies.&nbsp;<\/p>\n\n\n\n<p>Each gene of the complex has several variations.&nbsp;<\/p>\n\n\n\n<p>This allows the immune system to react to a wide range of foreign proteins.&nbsp;<\/p>\n\n\n\n<p>Some of these HLA genes are responsible for the immune system&#8217;s attack on the hair follicles.&nbsp;<\/p>\n\n\n\n<p>Besides HLA, other genes are also involved in inflammation and have been associated with <a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/understanding-alopecia\/\" target=\"_blank\" rel=\"noopener\" title=\"Alopecia\" data-wpil-keyword-link=\"linked\">Alopecia<\/a> Areata.<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"environmentnbsp\">Environment <\/h2>\n\n\n<p>In support of <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0190962298704992\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">evidence<\/a>, it is a fact that environmental triggers can cause autoimmune disorders.<\/p>\n\n\n\n<p>The factors such as chronic stress, hormones, sudden shocks, and disease conditions can stimulate the immune system to cause inflammation in hair follicles.&nbsp;<\/p>\n\n\n\n<p>Other factors include allergies, chemicals, seasonal changes, and skin injury, if any.&nbsp;<\/p>\n\n\n\n<p>Extreme <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4564047\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">stress<\/a> can trigger an immunological response by overproduction of free radicals.&nbsp;<\/p>\n\n\n\n<p>A 2015 <a href=\"https:\/\/bradscholars.brad.ac.uk\/bitstream\/handle\/10454\/17535\/zhangetal2019.pdf?sequence=2\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">estudiar<\/a> conducted in China found that Alopecia Areata was triggered in people with dust mite allergies.&nbsp;<\/p>\n\n\n\n<p>Physical injuries such as cuts, scrapes, and other types of damage on the scalp can also result in patchy hair loss.&nbsp;<\/p>\n\n\n\n<p>Despite all of this, these triggers only cause temporary damage to the scalp. This means that hair loss is temporary and hair regrowth is possible.<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"vitamin-d-deficiency\">Vitamin D deficiency<\/h2>\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/WowRxPharmacy.com\/wp-content\/uploads\/2023\/01\/Vitamin-deficiency-1024x536.webp\" alt=\"Causes of Alopecia Areata- Vitamin D deficiency\" class=\"wp-image-2415\"\/><figcaption class=\"wp-element-caption\">Vitamin D deficiency causes <a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/alopecia-areata\/\" target=\"_blank\" rel=\"noopener\" title=\"Alopecia Areata\" data-wpil-keyword-link=\"linked\">Alopecia Areata<\/a><\/figcaption><\/figure>\n\n\n\n<p>Dietary <a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/causes-of-alopecia-areata\/\" target=\"_blank\" rel=\"noopener\" title=\"causes of Alopecia Areata\" data-wpil-keyword-link=\"linked\">causes of Alopecia Areata<\/a> include a vitamin D deficiency.&nbsp;<\/p>\n\n\n\n<p>A 2020 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32772238\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">estudiar<\/a> states that vitamin D plays an important role in immune health.&nbsp;<\/p>\n\n\n\n<p>In deficient amounts, vitamin D can be linked to several immunological disorders, including Alopecia Areata.&nbsp;<\/p>\n\n\n\n<p>Keratinocytes in the skin metabolize vitamin D.&nbsp;<\/p>\n\n\n\n<p>These Keratinocytes are also responsible for processing keratin found in nails, hair, and skin.&nbsp;<\/p>\n\n\n\n<p>In cases of vitamin D deficiency, Keratinocytes in hair follicles are unable to <a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/how-to-prevent-hair-loss\/\" target=\"_blank\" rel=\"noopener\" title=\"prevent hair loss\" data-wpil-keyword-link=\"linked\">prevent hair loss<\/a> leading to Alopecia Areata.&nbsp;<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"medicationsnbsp\">Medications <\/h2>\n\n\n<p>Some of the medications used as therapy for other conditions can also stimulate Areata in the body.&nbsp;<\/p>\n\n\n\n<p>These medicines promote immune response, which can lead to inflammation in hair follicles to <a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/why-is-my-hair-falling-out\/\" target=\"_blank\" rel=\"noopener\" title=\"cause hair loss\" data-wpil-keyword-link=\"linked\">cause hair loss<\/a>.&nbsp;<\/p>\n\n\n\n<p>The medicines include,&nbsp;<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"nivolumab\">Nivolumab<\/h3>\n\n\n<p>Nivolumab belongs to the medical class of Monoclonal antibodies which are prescribed to cancer patients.&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8137334\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Studies<\/a> have shown that few cancer patients who took Nivolumab have developed Alopecia Areata.&nbsp;<\/p>\n\n\n<div class=\"su-box su-box-style-soft\" id=\"\" style=\"border-color:#073d11;border-radius:10px;\"><div class=\"su-box-title\" style=\"background-color:#3A7044;color:#FFFFFF;border-top-left-radius:8px;border-top-right-radius:8px\">Nivolumab-induced Hair Loss<\/div><div class=\"su-box-content su-u-clearfix su-u-trim\" style=\"border-bottom-left-radius:8px;border-bottom-right-radius:8px\">\nHair loss due to Nivolumab usually begins after a few months of therapy and is considered a positive sign of drug action.<br \/>\n<\/div><\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The condition is also called Nivolumab-induced Alopecia areata.<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"abacavir\">Abacavir<\/h3>\n\n\n<p>Abacavir is a reverse-transcriptase inhibitor that is prescribed as a treatment for HIV.&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4091366\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Evidence<\/a> supports that Abacavir can be a cause of a patchy bald scalp. The results have shown patchy hair loss in 5% of patients who received the immunotherapy.&nbsp;<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"fluvoxaminenbsp\">Fluvoxamina <\/h3>\n\n\n<p>Fluvoxamine is an antidepressant prescribed in patients with mental conditions such as Obsessive-Compulsive Disorder, anxiety, and depression.&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28763345\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Studies<\/a> support the claim that antidepressants like Fluvoxamine can be one of the causes of Alopecia Areata.&nbsp;<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"autoimmune-disordersnbsp\">Autoimmune Disorders <\/h2>\n\n\n<p>Autoimmune diseases are when the body&#8217;s immune system can&#8217;t differentiate between its cells and foreign invaders.&nbsp;<\/p>\n\n\n\n<p>Doctors have suggested that there can be a possibility of Alopecia Areata to occur with other autoimmune disorders such as Thyroid or Type 1 Diabetes.&nbsp;<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cAutoimmune conditions often travel in packs, so if you have one autoimmune disorder such as thyroid or diabetes, it is not uncommon to have others\u201d<\/p>\n<cite><a href=\"https:\/\/www.drbrookederm.com\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Brooke Jackson, MD<\/a>, a board-certified Dermatologist and Dermatologic surgeon<\/cite><\/blockquote>\n\n\n\n<p>Studies have also shown similar <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/ajmg.1320510313\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">results<\/a> where Type 1 and Type 2 diabetic patients were at an increased risk of Areata.&nbsp;<\/p>\n\n\n\n<p>Even the genetic actions <a href=\"https:\/\/medlineplus.gov\/genetics\/condition\/alopecia-areata\/#references\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">linked<\/a> with Alopecia Areata have been identified in people with other autoimmune disorders.<\/p>\n\n\n\n<p>It suggests that this disease may share some genetic risk factors.<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"who-is-at-risk-of-developing-alopecia-areata\">Who is at risk of developing Alopecia Areata?<\/h2>\n\n\n<p>Alopecia Areata can occur in people of any gender and race.&nbsp;<\/p>\n\n\n\n<p>The link between specific race and autoimmune disorders is still under study.&nbsp;<\/p>\n\n\n\n<p>There is <a href=\"https:\/\/www.uptodate.com\/contents\/alopecia-areata-beyond-the-basics\/print#:~:text=Approximately%201%20person%20in%2050,before%20the%20age%20of%2030\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">evidence<\/a> that most people develop Areata before 30.&nbsp;<\/p>\n\n\n\n<p>On the other hand, causes of Alopecia Areata can put some people at comparatively more risk than others of developing the disorder.&nbsp;<\/p>\n\n\n\n<p>People with a relative suffering from Areata are prone to developing patchy baldness.&nbsp;<\/p>\n\n\n\n<p>Others who may suffer from disorders such as Asthma, Vitiligo, Atopic Dermatitis, Thyroid disease, Down syndrome, and Hay fever can also get Areata.&nbsp;<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"conclusionnbsp\">Conclusi\u00f3n <\/h2>\n\n\n<p>Alopecia Areata is an autoimmune condition that results in hair loss due to your immune system attacking the hair follicles.&nbsp;<\/p>\n\n\n\n<p>Although the causes of Alopecia Areata are unknown, it is believed to be a result of genetic and environmental factors.<\/p>\n\n\n\n<p>A dermatologist can help diagnose Alopecia Areata and provide the best treatment options to <a class=\"wpil_keyword_link\" href=\"https:\/\/wowrxpharmacy.com\/es_co\/blog\/caida-del-cabello\/hair-growth-using-natural-herbs\/\" target=\"_blank\" rel=\"noopener\" title=\"promote hair growth\" data-wpil-keyword-link=\"linked\">promote hair growth<\/a>.<\/p>\n\n\n<div class=\"su-box su-box-style-soft\" id=\"\" style=\"border-color:#075380;border-radius:7px;\"><div class=\"su-box-title\" style=\"background-color:#3A86B3;color:#FFFFFF;border-top-left-radius:5px;border-top-right-radius:5px\">Recommended reading :<\/div><div class=\"su-box-content su-u-clearfix su-u-trim\" style=\"border-bottom-left-radius:5px;border-bottom-right-radius:5px\">You can read, <a href=\"https:\/\/WowRxPharmacy.com\/blog\/hair-loss\/alopecia-areata\/\" target=\"_blank\" rel=\"noopener\">What is Alopecia Areata? Understanding the Condition<\/a>, to learn more about Alopecia Areata, its signs, and treatments. <\/div><\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"frequently-asked-questionsnbsp\">Preguntas frecuentes <\/h2>\n\n<div id=\"rank-math-faq\" class=\"rank-math-block\">\n<div class=\"rank-math-list\">\n<div id=\"faq-question-1674308921474\" class=\"rank-math-list-item\">\n<h3 class=\"rank-math-question\">What causes Alopecia Areata?<\/h3>\n<div class=\"rank-math-answer\">\n\n<p>Alopecia Areata can be caused due to factors including genetic and environmental triggers. It is said to run in families and can also result from chronic stress, physical injury, or other autoimmune disorders like Vitiligo or Diabetes.\u00a0<\/p>\n\n<\/div>\n<\/div>\n<div id=\"faq-question-1674308933492\" class=\"rank-math-list-item\">\n<h3 class=\"rank-math-question\">What causes alopecia areata in a child?<\/h3>\n<div class=\"rank-math-answer\">\n\n<p>Alopecia Areata in children can be a result of hereditary factors. It usually runs in families and can be a result of genetic reasons.\u00a0<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"su-note\"  style=\"border-color:#cbcac8;border-radius:10px;-moz-border-radius:10px;-webkit-border-radius:10px;\"><div class=\"su-note-inner su-u-clearfix su-u-trim\" style=\"background-color:#E5E4E2;border-color:#ffffff;color:#36454F;border-radius:10px;-moz-border-radius:10px;-webkit-border-radius:10px;\"><strong>Citaciones:<\/strong><br \/>\n<a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/\" target=\"_blank\" rel=\"noopener\" title=\"WowRx\" data-wpil-keyword-link=\"linked\">WowRx<\/a> s\u00f3lo utiliza fuentes de alta calidad en la redacci\u00f3n de sus art\u00edculos. Por favor, lea nuestro <a href=\"https:\/\/WowRxPharmacy.com\/content-information-policy\" target=\"_blank\" rel=\"noopener\">pol\u00edtica de informaci\u00f3n sobre contenidos<\/a> para saber m\u00e1s sobre c\u00f3mo mantenemos nuestros contenidos fiables y dignos de confianza.<\/div><\/div>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25676427\/\" target=\"_blank\" rel=\"noopener nofollow\">Biran R, et al. The genetics of alopecia areata: new approaches, new findings, new treatments.<\/a>\n<\/li>\n<li><a href=\"https:\/\/europepmc.org\/article\/med\/25058999\" target=\"_blank\" rel=\"noopener nofollow\">Mahamid M, et al. Association between vitamin D levels and alopecia areata.<\/a><\/li>\n<li><a href=\"https:\/\/www.pennmedicine.org\/for-patients-and-visitors\/patient-information\/conditions-treated-a-to-z\/hair-loss-alopecia-areata\" target=\"_blank\" rel=\"noopener nofollow\">pennmedicine.org<\/a>\n<\/li>\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5573125\/\" target=\"_blank\" rel=\"noopener nofollow\"> Pratt, King et al. Alopecia areata. <\/a>\n<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Alopecia Areata is an autoimmune disorder that causes hair loss in patches.&nbsp; Hair loss is due to an immune system attack on the hair follicles.&nbsp; A study by Fricke and Miteva has shown that 2% of Areata affects 2% of the worldwide population.&nbsp; The causes of Alopecia Areata are complex and still under research.&nbsp; Experts [&hellip;]<\/p>","protected":false},"author":13,"featured_media":20441,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[1388],"tags":[1389,1390],"class_list":["post-20440","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hair-loss","tag-hairloss","tag-hairloss-causes"],"_links":{"self":[{"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/posts\/20440","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/comments?post=20440"}],"version-history":[{"count":1,"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/posts\/20440\/revisions"}],"predecessor-version":[{"id":25970,"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/posts\/20440\/revisions\/25970"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/media\/20441"}],"wp:attachment":[{"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/media?parent=20440"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/categories?post=20440"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/es_co\/wp-json\/wp\/v2\/tags?post=20440"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}