{"id":25580,"date":"2024-03-20T10:13:09","date_gmt":"2024-03-20T14:13:09","guid":{"rendered":"https:\/\/wowrxpharmacy.com\/blog\/uncategorized\/pmdd-treatment\/"},"modified":"2024-09-26T06:37:44","modified_gmt":"2024-09-26T10:37:44","slug":"pmdd-treatment","status":"publish","type":"post","link":"https:\/\/wowrxpharmacy.com\/de\/blog\/womens-health\/pmdd-treatment\/","title":{"rendered":"PMDD Treatment: Mitigating Symptoms and Severity"},"content":{"rendered":"<p>Premenstrual Dysphoric Disorder or PMDD is a severe form of Premenstrual Syndrome (PMS) listed as a disorder in DSM-5.&nbsp;<br><br>At this stage, symptoms like irritability, pain, anxiety, and even depression worsen, which can pose a challenge in daily life.&nbsp;<br><br>Such severity cannot be left unnoticed, so timely treatment is necessary.&nbsp;<br><br>Besides, initiating management on an individual level is also crucial to deal with the discomfort.&nbsp;<br><br>To find out more about PMDD treatment, including the options available and natural methods to mellow down the severity, follow through the article till the end.&nbsp;<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"premenstrual-dysphoric-disorder-treatment\">Premenstrual Dysphoric Disorder treatment<\/h2>\n\n\n<p>PMDD treatment is <a href=\"https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/premenstrual-dysphoric-disorder-pmdd#:~:text=PMDD%20is%20a%20serious%2C%20chronic%20condition%20that%20does%20need%20treatment.\" target=\"_blank\" rel=\"noopener\">essential<\/a> because the symptoms are so severe that they cannot be left untreated.&nbsp;<br><br>So, the aim of treatment remains to reduce the severity of <a href=\"https:\/\/wowrxpharmacy.com\/de\/blog\/womens-health\/pmdd-symptoms\/\">PMDD symptoms<\/a>.&nbsp;<br><br>For that, several options ranging from medications to surgeries are available.&nbsp;<\/p>\n\n\n<div class=\"su-box su-box-style-soft\" id=\"\" style=\"border-color:#073d11;border-radius:10px;\"><div class=\"su-box-title\" style=\"background-color:#3A7044;color:#FFFFFF;border-top-left-radius:8px;border-top-right-radius:8px\">Tatsache:<\/div><div class=\"su-box-content su-u-clearfix su-u-trim\" style=\"border-bottom-left-radius:8px;border-bottom-right-radius:8px\">About 90 percent of the women of reproductive age  <a class=\"wpil_keyword_link\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6964059\/#:~:text=Altogether%20results%20show%2C%20that%20up%20to%2090%25%20of%20women%20of%20reproductive%20age%20experience%20several%20premenstrual%20symptoms%20varying%20from%20mild%20to%20severe%3B%20around%2020%E2%80%9340%25%20of%20them%20experience%20PMS%2C%20and%202%E2%80%938%25%20suffer%20from%20premenstrual%20dysphoric%20disorder%20(PMDD)\" target=\"_blank\" rel=\"noopener nofollow\" title=\"experience\" data-wpil-keyword-link=\"linked\">experience<\/a> premenstrual symptoms ranging from mild to severe. Out of these, 20-40 percent have PMS, while 2-8 percent develop PMDD.<\/div><\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"selective-serotonin-reuptake-inhibitors-ssrisnbsp\">Selective Serotonin Reuptake Inhibitors (SSRIs) <\/h3>\n\n\n<p>SSRIs are antidepressants recommended for a wide range of problems.&nbsp;<br><br>They are the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10074750\/#:~:text=SSRIs%20are%20a,%2C%202015).\" target=\"_blank\" rel=\"noopener\">first-line<\/a> treatment for PMDD used for managing symptoms related to mood.&nbsp;<br><br>Instead of a regular dosage, SSRIs for PMDD are recommended intermittently.&nbsp;<br><br>So, the medications are only taken in the second half of the menstrual cycle.&nbsp;<br><br>This is done to effectively manage the symptoms, which avoids long-term withdrawal syndrome that can occur from daily use.&nbsp;<br><br>Doctors may <a href=\"https:\/\/www.health.harvard.edu\/womens-health\/treating-premenstrual-dysphoric-disorder#:~:text=Antidepressants%20that%20slow%20the%20reuptake%20of%20serotonin%20are,have%20not%20proven%20effective%20in%20treating%20PMDD.%20This\" target=\"_blank\" rel=\"noopener\">prescribe<\/a> SSRIs like Fluoxetine (Prozac) and Sertraline (Zoloft) for PMDD treatment.&nbsp;<br><br>They work by slowing the reuptake of Serotonin.&nbsp;<br><br>Other antidepressants which target other neurotransmitters besides Serotonin are not effective for PMDD.&nbsp;<\/p>\n\n\n<div class=\"su-box su-box-style-soft\" id=\"\" style=\"border-color:#7a1312;border-radius:10px;\"><div class=\"su-box-title\" style=\"background-color:#AD4645;color:#FFFFFF;border-top-left-radius:8px;border-top-right-radius:8px\">Warnung:<\/div><div class=\"su-box-content su-u-clearfix su-u-trim\" style=\"border-bottom-left-radius:8px;border-bottom-right-radius:8px\">SSRIs such as Prozac and Zoloft can  <a class=\"wpil_keyword_link\" href=\"https:\/\/www.nhs.uk\/mental-health\/talking-therapies-medicine-treatments\/medicines-and-psychiatry\/ssri-antidepressants\/side-effects\/#:~:text=Serotonin%20syndrome%20is,loss%20of%20consciousness\" target=\"_blank\" rel=\"noopener nofollow\" title=\"cause\" data-wpil-keyword-link=\"linked\">cause<\/a> Serotonin Syndrome, resulting in sweating, shivering, diarrhea, seizures, and irregular heartbeat. So the self-prescription of the drug must be strictly avoided, and when prescribed by the doctor, the dosage must be adhered to for avoiding complications.\u00a0 <\/div><\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"benzodiazepinesbzdsnbsp\">Benzodiazepines(BZDs) <\/h2>\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/wowrxpharmacy.com\/wp-content\/uploads\/2023\/07\/menopause-and-depression-1024x576.webp\" alt=\"depression\" class=\"wp-image-10612\"\/><figcaption class=\"wp-element-caption\">Depressed woman in her mid 40&#8217;s sitting alone in room <\/figcaption><\/figure>\n\n\n\n<p>Alprazolam is one of the BSZs used for PMDD treatment.&nbsp;<br><br>A <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3299178\/#:~:text=Alprazolam%200.25%20mg,to%20other%20therapies.\" target=\"_blank\" rel=\"noopener\">study<\/a> by S Smith found that Alprazolam was effective in reducing the severity of menstrual symptoms.&nbsp;<br><br>It administered 0.25 mg thrice daily for 20 days till the second day of the menstrual cycle.&nbsp;<br><br>After this, the tablet was reduced to one a day to prevent withdrawal symptoms.&nbsp;<br><br>The benefits included relieved symptoms which included:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Premenstrual nervous tension<\/li>\n\n\n\n<li>Stimmungsschwankungen<\/li>\n\n\n\n<li>Irritability<\/li>\n\n\n\n<li>Anxiety<\/li>\n\n\n\n<li>Depression<\/li>\n\n\n\n<li>Erm\u00fcdung<\/li>\n\n\n\n<li>Forgetfulness<\/li>\n\n\n\n<li>Crying<\/li>\n\n\n\n<li>Cravings for sweets<\/li>\n\n\n\n<li>Abdominal bloating<\/li>\n\n\n\n<li>Abdominal cramps<\/li>\n\n\n\n<li>Kopfschmerzen<\/li>\n<\/ul>\n\n\n<h3 class=\"wp-block-heading\" id=\"cognitive-behavioral-therapy-cbt\">Cognitive Behavioral Therapy (CBT)<\/h3>\n\n\n<p>CBT is a talking therapy that alters the way of thinking and behavior to manage problems.&nbsp;<br><br>It can <a href=\"https:\/\/www.mind.org.uk\/information-support\/types-of-mental-health-problems\/premenstrual-dysphoric-disorder-pmdd\/treatment\/#:~:text=To%20help%20manage,and%20depression.\" target=\"_blank\" rel=\"noopener\">help<\/a> women with PMDD as it can manage symptoms such as anxiety and depression.&nbsp;<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"birth-control-pills\">Antibabypillen<\/h3>\n\n\n<p>Oral contraceptives, also called birth control pills, are <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532307\/#:~:text=Oral%20contraceptive%20pills,anti%2Dandrogenic%20effects.\" target=\"_blank\" rel=\"noopener\">gebraucht<\/a> in clinical practice to treat PMDD.&nbsp;<br><br><a href=\"https:\/\/wowrxpharmacy.com\/de\/blog\/sexual-health\/birth-control-pills\/\">Antibabypillen<\/a> with fewer hormone-free days can be more beneficial in controlling hormone-related symptoms.&nbsp;<br><br>Drospirenone is particularly effective in treating PMDD symptoms because of its anti-aldosterone and anti-androgenic effects.<br><br>Yaz for PMDD treatment is the <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19936169\/#:~:text=The%20combined%20oral,benefits%20are%20discussed.\" target=\"_blank\" rel=\"noopener\">only<\/a> approved birth control pill by the FDA so far.&nbsp;<br><br>It is a combination of Drospirenone 3mg with Ethinylestradiol 20 mug.&nbsp;<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/wowrxpharmacy.com\/wp-content\/uploads\/2024\/01\/Yasmin-birth-control-pills.webp\" alt=\" class=\"wp-image-17720\"><\/figure>\n\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\" style=\"font-size:26px\" id=\"are-pmdd-symptoms-bothering-you\">Are PMDD symptoms bothering you?<\/h4>\n\n\n<p class=\"has-text-align-center\">Head to <a href=\"https:\/\/wowrxpharmacy.com\/de\/\">WowRx<\/a> to bag an ideal birth control for relieving symptoms and simultaneous pregnancy prevention.<br><\/p>\n\n\n\n<a class=\"gb-button gb-button-faf8176f gb-button-text\" href=\"https:\/\/wowrxpharmacy.com\/de\/product\/yasmin-3mg\/\" target=\"_blank\" rel=\"noopener noreferrer\">Yasmin 3 mg<\/a>\n\n\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"gonadotropinreleasing-hormone-analogs-gnrha\">Gonadotropin-releasing Hormone Analogs (GnRHa)<\/h3>\n\n\n<p>When birth control pills or SSRIs do not work, GnRHa can be used to relieve symptoms.&nbsp;<br><br>Even though it is <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37341478\/#:~:text=When%20first%2D%20and%20second%2Dline%20treatments%20have%20failed%20to%20yield%20symptom%20relief%2C%20the%20use%20of%20GnRHa%20with%20hormone%20addback%20should%20be%20considered.\" target=\"_blank\" rel=\"noopener\">gebraucht<\/a> when the first-line treatment for PMDD fails, they are still very effective when used with hormone add back therapy.&nbsp;<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"danazol\">Danazol<\/h3>\n\n\n<p>It is a synthetic partial Androgen antagonist\/agonist and gonadotropin inhibitor that can <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2404119\/#:~:text=use%20of%20Danocrine,or%20anxiety%20symptomatology.\" target=\"_blank\" rel=\"noopener\">reduce<\/a> the severity of PMS symptoms.&nbsp;<br><br>So, it can benefit in the case of PMDD but is not a suitable option if anxiety and depression are the primary symptoms.&nbsp;<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"hysterectomy\">Hysterectomy<\/h3>\n\n\n<p>Another <a href=\"https:\/\/iapmd.org\/surgical-menopause#:~:text=While%20many%20people%20refer%20to%20surgery%20for%20PMDD\/PME%20as%20a%20%E2%80%98hysterectomy%E2%80%99%20(removal%20of%20the%20uterus)%20%2D%20the%20essential%20part%20of%20the%20procedure%20is%20actually%20the%20removal%20of%20both%20ovaries%20(bilateral%20oophorectomy%20%2D%20or%20bilateral%20salpingo%20oophorectomy%20if%20the%20fallopian%20tubes%20are%20also%20removed).\" target=\"_blank\" rel=\"noopener\">option<\/a> for PMDD treatment, Hysterectomy, is a surgical procedure.&nbsp;<br><br>It involves uterus removal alongside both ovaries for treating PMDD.&nbsp;<br><br>As the ovarian cycle is what triggers mood changes, just removing the uterus alone is not suitable for PMDD treatment.&nbsp;<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"new-pmdd-treatments\">New PMDD treatments<\/h3>\n\n\n<p>Balancing Progesterone for PMDD treatment can help manage symptoms.&nbsp;<br><br>So, the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9066446\/#:~:text=Thus%2C%20new%20therapeutic,system%20with%20sepranolone.\" target=\"_blank\" rel=\"noopener\">latest<\/a> approach is to inhibit Progesterone receptors, which can be achieved through Ulipristal Acetate.&nbsp;<br><br>Another medication called Dutasteride reduces the conversion of Progesterone into Allopregnanolone (its metabolite).&nbsp;<br><br>Moreover, Sepranolone can control the impact of Allopregnanolone on the main inhibitory neurotransmitter system.&nbsp;<br><br>All these methods need further studies to develop therapies for PMDD treatment and associated risks.&nbsp;<\/p>\n\n\n<h3 class=\"wp-block-heading\" id=\"nonpharmacological-methods\">Non-Pharmacological Methods<\/h3>\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/wowrxpharmacy.com\/wp-content\/uploads\/2023\/11\/high-featured-2-1024x576.webp\" alt=\"pmdd treatment\" class=\"wp-image-15567\"\/><figcaption class=\"wp-element-caption\">woman doing yoga and meditation<\/figcaption><\/figure>\n\n\n\n<p>These methods include <a href=\"https:\/\/wowrxpharmacy.com\/de\/blog\/womens-health\/pmdd-natural-treatment\/\">natural treatments for PMDD<\/a>.&nbsp;<br><br>Firstly, exercise is <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532307\/#:~:text=Non%2DPharmacological%20Methods,yoga\/%20breathing%20techniques.\" target=\"_blank\" rel=\"noopener\">important<\/a> to regulate Beta-endorphin levels.&nbsp;<br><br>Relaxation techniques like meditation, yoga, and breathing exercises are also helpful management tools for PMDD.<br><br>Herbs like Chasteberry have also been proven beneficial due to their dopaminergic effect.&nbsp;<br><br>Moreover, focusing on diet can also help, as calcium and vitamin B6 can improve emotional and physical symptoms.<br><br>To know more in detail, read this self-care guide on the role of <a href=\"https:\/\/wowrxpharmacy.com\/de\/blog\/womens-health\/vitamins-for-pmdd\/\">vitamins for PMDD<\/a> treatment.&nbsp;<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"conclusion\">Abschluss<\/h2>\n\n\n<p>PMDD is a severe form of PMS which causes pain and emotional distress, affecting daily life.&nbsp;<br><br>As it was also recently listed as a disorder in DSM-5, PMDD treatment becomes even more vital, looking at its impact on female health.&nbsp;<br><br>Mostly, its treatment options are pharmacological methods, including medications such as SSRIs and oral contraceptives, along with surgical options like Hysterectomy.&nbsp;<br><br>The non-pharmacological approach involves focusing on diet and exercise.&nbsp;<br><br>With a cooperative approach to treatment by a medical professional and self-help strategies, the symptoms and discomfort of PMDD can be managed effectively for a better outcome.&nbsp;<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"frequently-asked-questions\">H\u00e4ufig gestellte Fragen<\/h2>\n\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"su-note\"  style=\"border-color:#cbcac8;border-radius:10px;-moz-border-radius:10px;-webkit-border-radius:10px;\"><div class=\"su-note-inner su-u-clearfix su-u-trim\" style=\"background-color:#E5E4E2;border-color:#ffffff;color:#36454F;border-radius:10px;-moz-border-radius:10px;-webkit-border-radius:10px;\"><strong>Zitate:<\/strong><br \/>\n<a class=\"wpil_keyword_link\" href=\"https:\/\/WowRxPharmacy.com\/\" target=\"_blank\" rel=\"noopener\" title=\"WowRx\" data-wpil-keyword-link=\"linked\">WowRx<\/a> verwendet beim Schreiben unserer Artikel nur hochwertige Quellen. Bitte lesen Sie unsere <a href=\"https:\/\/wowrxpharmacy.com\/de\/inhaltsinformationsrichtlinie\/\" target=\"_blank\" rel=\"noopener\">Inhaltsinformationsrichtlinie<\/a> um mehr dar\u00fcber zu erfahren, wie wir die Zuverl\u00e4ssigkeit und Vertrauensw\u00fcrdigkeit unserer Inhalte gew\u00e4hrleisten.<\/div><\/div>\n<ul class=\"citations\">\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532307\/\" target=\"_blank\" rel=\"noopener nofollow\">ncbi.nlm.nih.gov<\/a><\/li>\n<li><a href=\"https:\/\/www.health.harvard.edu\/womens-health\/treating-premenstrual-dysphoric-disorder\" target=\"_blank\" rel=\"noopener nofollow\">health.harvard.edu<\/a><\/li>\n<li><a href=\"https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/premenstrual-dysphoric-disorder-pmdd\" target=\"_blank\" rel=\"noopener nofollow\">hopkinsmedicine.org<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Premenstrual Dysphoric Disorder or PMDD is a severe form of Premenstrual Syndrome (PMS) listed as a disorder in DSM-5.&nbsp; At this stage, symptoms like irritability, pain, anxiety, and even depression worsen, which can pose a challenge in daily life.&nbsp; Such severity cannot be left unnoticed, so timely treatment is necessary.&nbsp; Besides, initiating management on an [&hellip;]<\/p>","protected":false},"author":13,"featured_media":25581,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[528],"tags":[1476,1673,1670],"class_list":["post-25580","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-womens-health","tag-pmdd","tag-pmdd-symptoms","tag-pmdd-treatment"],"_links":{"self":[{"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/posts\/25580","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/comments?post=25580"}],"version-history":[{"count":1,"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/posts\/25580\/revisions"}],"predecessor-version":[{"id":28530,"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/posts\/25580\/revisions\/28530"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/media\/25581"}],"wp:attachment":[{"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/media?parent=25580"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/categories?post=25580"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wowrxpharmacy.com\/de\/wp-json\/wp\/v2\/tags?post=25580"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}